Why living donation matters
There are ~6,000 people on the UK kidney transplant waiting list with an average wait of 2.5–3 years on dialysis. Living donation:
- Cuts waiting time to months not years
- Allows pre-emptive transplant (before dialysis ever starts)
- Gives the recipient ~20 years of graft function vs 12 from a deceased donor
- Allows planned surgery rather than emergency 4am call
- Often involves a relative, partner, friend or altruistic stranger
The UK Living Kidney Sharing Scheme (UKLKSS) matches incompatible donor-recipient pairs in chains of up to 3 swaps so almost everyone willing to donate can help someone.
Who can donate?
Eligibility
- Adult 18+ (no upper age limit if fit — 70s and 80s have donated)
- Two healthy kidneys (confirmed by GFR & CT)
- BMI ideally <30 (some centres accept up to 35)
- Blood pressure normal or well-controlled on minimal medication
- No diabetes (pre-diabetes assessed case by case)
- No active cancer (5+ years clear for most cancers)
- No untreated mental health condition
- Non-smoker preferred (must stop at least 8 weeks before)
- Capacity to give informed consent (HTA assessment)
ABO-incompatible and HLA-incompatible donation is now possible at most UK centres with desensitisation.
The assessment journey
Typical UK Pathway
- Initial enquiry → transplant centre living donor coordinator
- Blood group + tissue typing (cross-match with recipient)
- Health screen — BP, urine, ECG, chest X-ray, blood tests
- GFR measurement (isotope or 24h urine)
- CT angiogram of kidneys & blood vessels
- Psychological assessment
- Independent HTA assessor interview (legal requirement)
- Multidisciplinary team approval
- Final pre-op clinic with surgeon & anaesthetist
- Surgery date set
At every step you can withdraw — no questions asked. Confidentiality is absolute.
Kidney Vitality is a daily multivitamin developed by a UK Consultant Nephrologist using renal nutrition principles. It contains no added potassium, magnesium, phosphorus or iron, and no herbal blends. See the formulation.
The operation & recovery
Surgery
- Laparoscopic (keyhole) nephrectomy in ~95% of UK cases
- 3–4 small abdominal incisions + one slightly larger to remove the kidney
- 2–3 hour operation under general anaesthetic
- Hospital stay: 2–4 nights
Recovery
- Week 1: significant fatigue, mild pain (paracetamol + short opioid course)
- Weeks 2–4: gradual return to walking, light activity
- Weeks 4–6: most office workers back at work
- Weeks 8–12: full recovery; heavy lifting, sport, manual work
- 3 months: post-op renal scan and bloods
Risks (rare):
- Death: ~1 in 3,000
- Bleeding requiring transfusion: ~1%
- Wound infection: ~3%
- Conversion to open surgery: ~1%
- Long-term risk of CKD requiring dialysis: ~0.5% lifetime
Life after donation
Follow-up
- Annual GP/transplant centre check: BP, urine ACR, creatinine
- Lifelong — never stop attending
- Lifestyle: maintain healthy BMI, avoid NSAIDs lifelong, BP <130/80
- Pregnancy is safe but with closer monitoring
- Insurance: donors have full life and travel insurance access
- Many donors describe the experience as the most rewarding of their life
The NHS Blood and Transplant donor reimbursement scheme covers:
- Travel to appointments
- Loss of earnings (capped)
- Childcare costs during recovery
- Accommodation if travelling for surgery
How to start
- Speak to the recipient's transplant centre — every UK centre has a living donor coordinator.
- Or contact Give a Kidney (giveakidney.org) for altruistic (non-directed) donation.
- Free, confidential, no pressure.
- UK transplant centres: Royal Free, Guy's, Hammersmith (London); Manchester Royal Infirmary; Cardiff; Edinburgh Royal; Glasgow Queen Elizabeth; Belfast City; Newcastle Freeman; Leeds St James; Birmingham Queen Elizabeth; Sheffield; Bristol; Liverpool Royal; Nottingham; Oxford Churchill; Plymouth; Portsmouth; Coventry; Cambridge.
More info: NHS Blood and Transplant — odt.nhs.uk/living-donation





