Some supplements that are perfectly safe for the general adult population are not safe in chronic kidney disease. Here is the UK reference list.
Vitamins to avoid or limit
- High-dose vitamin A — accumulates in CKD; avoid supplements above RNI.
- High-dose vitamin C (above 1000 mg) — increases oxalate stone risk.
- High-dose vitamin E — not recommended for the general UK population.
Minerals to avoid or limit
- Potassium — never supplement without specialist advice.
- Phosphate / phosphoric acid additives — worsen renal bone disease.
- Magnesium-based laxatives and antacids — accumulate in CKD.
Herbal supplements to avoid
The NHS and Kidney Care UK specifically warn against:
- Aristolochia (linked to kidney failure and urinary tract cancer).
- St John's Wort (interacts with ciclosporin and many other renal medications).
- Ginseng, liquorice root, noni juice — all reported to affect blood pressure or potassium.
"Detox" and "kidney cleanse" products
The NHS is unambiguous: there is no scientific evidence for "kidney detox" or "kidney cleanse" supplements. Avoid them.
What to do instead
Stick to a kidney-conscious daily supplement with moderate doses, no added potassium, no added phosphate and no megavitamins — and discuss any new supplement with your GP or renal team first.